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assisted zona hatching
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Ensemble des techniques microchirurgicales destinées à pratiquer une ouverture au niveau de la zone pellucide en vue de favoriser l'éclosion du blastocyste et d'améliorer le taux d'implantation. (Source : INRA)
(fr)
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Les ouvertures de la zone pellucide peuvent être effectuées de différentes façons : - mécaniquement au moyen de micro-pipettes ; - chimiquement au moyen d'une solution de Tyrode acide ; - ou encore au moyen d'un faisceau laser. (Source : INRA)
(fr)
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Successful hatching of the embryo is a prerequisite for its implantation in the uterus. Failure of ZP rupture and subsequent impaired hatching account at least in part for the relatively low implantation rates of embryos resulting from IVF. This may be due to the loss of elasticity (hardening) of the ZP after in vitro culture and in vivo aging. This led to the adoption of assisted hatching techniques in which breaching of the ZP is performed to promote the natural process of hatching. Digestion by acidic Tyrode's solution is the most widely used technique even though it involves the use of a strong chemical agent. (Source : INRA)
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assisted hatching
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éclosion embryonnaire assistée
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Biologie de la reproduction
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Gynecology and obstetrics
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Gynécologie et obstétrique
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Reproduction biology
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